drugset / Trial / NCT04695483

Reduction of Progesterone Elevation at Trigger in POR After Long Acting COS Compared With Daily COS: a Prospective Randomized Trial

NCT04695483

Phase 4 Completed 110 enrolled IRCCS San Raffaele
RandomizedParallel-groupOpen-labelPrevention

Summary

The overarching objective of this research is to generate clinical evidence to argue the benefits of long acting stimulation protocol compared to the daily stimulation protocol in poor ovarian responder bologna' criteria patients after controlled ovarian stimulation. Reduction in the proportion of subjects with progesterone \> 1.1 ng/ml on the day of triggering (day + 13) in the experimental group compared to the control group is expected.

Timeline

Start
2022-02-22
Primary completion
2024-01-19
Completion
2024-05-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Corifollitropin alfa Protein / enzyme biologic
Subject Follitropin beta Protein / enzyme biologic

Indications