drugset / Trial / NCT04696029

DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma

NCT04696029

Phase 2 Recruiting 118 enrolled Giselle Sholler
NaSingle-groupOpen-labelTreatment

Summary

Difluoromethylornithine (DFMO) will be used in an open label, multicenter, study as Maintenance Therapy for Molecular High Risk/Very High Risk and Relapsed/Refractory Medulloblastoma.

Timeline

Start
2021-03-29
Primary completion
2028-03
Completion
2029-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Eflornithine Small molecule 2500 mg/m2 Oral

Indications