drugset / Trial / NCT04696783

The Effect of PPI in Preventing Gastroesophageal Reflux Disease of Seafarers

NCT04696783

RandomizedSingle-groupOpen-labelPrevention

Summary

In view of the high incidence of GERD among seafarers and its continuing impact on the life quality of seafarers, it is necessary to use preventive treatment. At the same time, because both mental and psychological factors and changes in intestinal flora may play a certain role in the development and treatment of GERD, this project intends to take the seafarers involved in this scientific expedition as the participants to explore the effect of PPI discontinuous therapy in preventing gastroesophageal reflux disease of seafarers, a special occupational group and the changes in the mental and psychological status and intestinal flora of this group of people after PPI therapy.

Timeline

Start
2021-07
Primary completion
2021-09
Completion
2021-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Esomeprazole Small molecule