drugset / Trial / NCT04697121

Artichoke and Bergamot Phytosome

NCT04697121 ↗

RandomizedParallel-groupTriple-blindTreatment

Summary

According to WHO data, about 50% of deaths each year are caused by cardiovascular disease. One of the strategies for prevention of cardiovascular diseases, in addition to a correct lifestyle, is to implement therapies that reduce the level of cholesterol in the blood and at the same time control the glycemic levels, which are closely related in the maintenance of metabolic homeostasis. The aim of this clinical study is to confirm the potential broader activity as hypocholesterolemic agent in bergamot poor-responders subjects with mild hypercholesterolemia. The study was a 8-week randomized double-blind placebo-controlled trial. Participants were randomized to either the supplement based on dry extract from artichoke leaf and bergamot phospholipid (31) or placebo arm (29).

Timeline

Start
2019-02-21
Primary completion
2020-07-02
Completion
2020-07-16

Drugs

EvaluationDrugModalityDoseRoute
Subject Artichoke leaf standardized dry extract Unknown 100 mg Oral
Subject Bergamot Phytosome Unknown 600 mg Oral

Indications