drugset / Trial / NCT04697953

Efficacy and Safety of Brolucizumab 6mg in a Treat and Extend Regimen in Patients With Neovascular Age-Related Macular Degeneration (nAMD) With Prior Anti-VEGF Exposure (PEREGRINE)

NCT04697953

Phase 3 Withdrawn Novartis Pharmaceuticals
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to assess whether switching nAMD patients from aflibercept to brolucizumab would permit extension of treatment intervals while maintaining treatment efficacy, thereby alleviating the treatment burden on patients, caregivers, healthcare professionals (HCPs), and medical institutions.

Timeline

Start
2021-05-31
Primary completion
2021-06-21
Completion
2025-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Brolucizumab Other / unclassified 6 mg Intravitreal