drugset / Trial / NCT04705129

Zanubrutinib Combined With Tislelizumab in the Treatment of r/r PMBCL and EBV+ DLBCL

NCT04705129 ↗

Phase 2 Unknown 40 enrolled Ruijin Hospital
NaSingle-groupOpen-labelTreatment

Summary

The study is to investigate the safety and efficacy of Zanubrutinib combined with Tislelizumab in the treatment of relapsed/refractory primary mediastinal large B-cell lymphoma and Epstein-Barr Virus-positive diffuse large B-cell lymphoma.

Timeline

Start
2021-01-01
Primary completion
2023-01-01
Completion
2024-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Tislelizumab Monoclonal antibody 200 mg Intravenous
Subject Zanubrutinib Small molecule 160 mg Oral