A Study of Single Ascending Dose of LEM-S401 in Healthy Participants

Summary

The primary objective of the study is to assess the safety and tolerability of single dose of LEM-S401 in healthy adult subjects.

Timeline

Start

2022-07-11

Primary completion

2022-10-18

Completion

2023-02-03

Publications

• Kim HY, Cho J, Park MK, Min DH, Hwang JG, Won C. A First-In-Human Phase 1 Study to Evaluate the Safety and Tolerability of LEM-S401, a Novel siRNA-DegradaBALL Drug Targeting CTGF in Healthy Adults. Clin Transl Sci. 2025 Apr;18(4):e70207. doi: 10.1111/cts.70207.

Drugs

Indications