drugset / Trial / NCT04707248

A Study of DS-6000a in Subjects With Advanced Renal Cell Carcinoma and Ovarian Tumors

NCT04707248

Phase 1 Active not recruiting 179 enrolled Daiichi Sankyo Merck Sharp & Dohme LLC · collab
Non-randomizedSequentialOpen-labelTreatment

Summary

This clinical trial will evaluate raludotatug deruxtecan (R-DXd; DS-6000a) in participants with advanced renal cell carcinoma (RCC) and ovarian cancer (OVC). The main goals of this study will be to investigate the recommended dose of R-DXd that can be given safely to participants, assess the adverse events of R-DXd, and evaluate the effectiveness of R-DXd.

Timeline

Start
2020-12-22
Primary completion
2026-04-30
Completion
2026-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Raludotatug Deruxtecan Other / unclassified 1.6 mg/kg Intravenous