Multiple Ascending Dose Study of HU6 in High BMI Volunteers

Summary

This is a 14-day multiple ascending dose trial in high BMI volunteers in up to 4 cohorts of 10 high BMI volunteers each consisting of 8 receiving HU6 and 2 receiving placebo. Upon review of the safety and PK data, it may be decided to expand the current cohort size and/or dose escalate to the next cohort. In addition, the sponsor may elect not to enroll all 4 cohorts based on safety and/or PK and/or PD data, or enlist an additional cohort at a higher dose if deemed safe.

Timeline

Start

2021-01-04

Primary completion

2021-04-30

Completion

2021-07-30

Drugs

Indications