drugset / Trial / NCT04722146

A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma

NCT04722146

Phase 1 Active not recruiting 140 enrolled Janssen Research & Development, LLC
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to characterize the safety and tolerability of teclistamab when administered in different combination regimen and to identify the optimal dose(s) of teclistamab combination regimens.

Timeline

Start
2021-03-12
Primary completion
2025-10-03
Completion
2027-10-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Teclistamab Monoclonal antibody
Background Bortezomib Small molecule
Background Daratumumab Monoclonal antibody
Background Lenalidomide Other / unclassified
Background Nirogacestat Small molecule
Background Pomalidomide Other / unclassified

Indications