drugset / Trial / NCT04726046

Effectiveness of Prophylactic Antibiotics Therapy in Laparoscopic Cholecystectomy on Infection Rate

NCT04726046

Phase 1 Completed 529 enrolled Chonbuk National University Hospital
RandomizedParallel-groupSingle-blindPrevention

Summary

529 patients performed elective LCC at Chonbuk National University Hospital between April 2014 and August 2015. Total 509 patients were enrolled by inclusion criteria. They were randomized studied by comparing with antibiotic group (n=249, AG, cefotetan 1g, 1 dose/prophylactic) and non-antibiotic group (n=260, NAG) by table of random numbers. The clinical variables were pre and post-operatively blood tests enclude WBC, ESR, CRP, body temperatures, symptoms and imaging of chest x-ray to evaluate the infections.

Timeline

Start
2014-04-01
Primary completion
2015-08-01
Completion
2017-09-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Cefotetan Small molecule 1 g

Indications