Respiratory Impact of LA Volume After IS Block

Phase 4 Completed 60 enrolled Eric Albrecht

RandomizedParallel-groupTriple-blindTreatment

Summary

The hypothesis of this study is that a reduced extrafascial volume of local anesthetic for an interscalene brachial plexus block is associated with a lower incidence of diaphragmatic hemiparalysis after an arthroscopic surgery of the shoulder, without any reduction of the analgesic efficacy.

Timeline

Start: 2021-02-01
Primary completion: 2023-11-20
Completion: 2023-11-20

Publications

Renard Y, Grape S, Gonvers E, Rossel JB, Goetti P, Albrecht E. Respiratory impact of local anaesthetic volume after interscalene brachial plexus block with extrafascial injection: a randomised controlled double-blinded trial. Br J Anaesth. 2025 Apr;134(4):1153-1160. doi: 10.1016/j.bja.2024.12.010. Epub 2025 Jan 23.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Ropivacaine	Other / unclassified	10 ml	Other
Comparator	Ropivacaine	Other / unclassified	20 ml	Other

Indications

No indication recorded.