drugset / Trial / NCT04727554
Study of AMG 994 Monotherapy and AMG 994 and AMG 404 Combination Therapy in Participants With Advanced Solid Tumors
Non-randomizedSequentialOpen-labelTreatment
Summary
The primary objective of this study is to evaluate the safety, tolerability, and maximum tolerated dose (MTD)/maximum tolerated combination dose (MTCD) or recommended phase 2 dose (RP2D) of AMG 994 as monotherapy and AMG 994 in combination with AMG 404 in participants with advanced solid tumors.
Timeline
- Start
- 2021-04-29
- Primary completion
- 2023-06-05
- Completion
- 2023-06-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AMG 404 | Monoclonal antibody | — | Intravenous |
| Subject | AMG 994 | Unknown | — | Intravenous |