drugset / Trial / NCT04727554

Study of AMG 994 Monotherapy and AMG 994 and AMG 404 Combination Therapy in Participants With Advanced Solid Tumors

NCT04727554

Phase 1 Completed 11 enrolled Amgen
Non-randomizedSequentialOpen-labelTreatment

Summary

The primary objective of this study is to evaluate the safety, tolerability, and maximum tolerated dose (MTD)/maximum tolerated combination dose (MTCD) or recommended phase 2 dose (RP2D) of AMG 994 as monotherapy and AMG 994 in combination with AMG 404 in participants with advanced solid tumors.

Timeline

Start
2021-04-29
Primary completion
2023-06-05
Completion
2023-06-05

Drugs

EvaluationDrugModalityDoseRoute
Subject AMG 404 Monoclonal antibody Intravenous
Subject AMG 994 Unknown Intravenous

Indications