Study of Irinotecan Liposome Injection in Patients With Advanced Breast Cance

Summary

This study is an open-label, single-arm, phase I study of irinotecan liposome injection in patients with advanced breast cancer. The purpose of this study is to evaluate the safety, efficacy and pharmacokinetics of irinotecan liposome injection in patients with advanced breast cancer.

Timeline

Start

2021-05-31

Primary completion

2023-06-05

Completion

2024-06-05

Publications

• Fan Y, Zhang Q, Yan M, Qu X, Yin Y, Sun T, Yang J, Wang Y, Wang X, Niu Z, Wang X, Sun S, Zhao W, Liu Y, Niu M, Zhao X, Xu B. Intravenous liposomal irinotecan in metastatic triple-negative breast cancer after >/= 2 prior lines of chemotherapy: a phase Ib study. Nat Commun. 2025 Jan 2;16(1):3. doi: 10.1038/s41467-024-55090-4.

Drugs

Indications