drugset / Trial / NCT04730193

Caffeine and Cerebrovascular Reactivity

NCT04730193

Phase 0 Completed 10 enrolled University of Oklahoma
RandomizedCrossoverTriple-blindOther

Summary

Caffeine is the most commonly used stimulant drug with well documented effects on cerebral vascula-ture. Caffeine is known to non-specifically bind to adenosine receptors in the brain and to reduce resting blood flow while improving attention and cognitive function, which suggests that it may allow a more efficient dynamic blood flow regulation through neurovascular coupling. This study will use standardized dose of caffeine to test its effect on NVC responses in cerebral and retinal arterioles.

Timeline

Start
2021-02-01
Primary completion
2022-08-01
Completion
2022-08-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Caffeine Small molecule 100 mg

Indications

No indication recorded.