drugset / Trial / NCT04733183
Efficacy and Safety of L19TNF in Previously Treated Patients with Advanced Stage or Metastatic Soft-tissue Sarcoma
RandomizedParallel-groupOpen-labelTreatment
Summary
Open label, randomized, controlled phase II study preceded by a safety run-in part in subjects with advanced or metastatic soft-tissue sarcoma.
Timeline
- Start
- 2020-08-28
- Primary completion
- 2025-12
- Completion
- 2025-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dacarbazine | Small molecule | 850 mg/m2 | — |
| Subject | Dacarbazine | Small molecule | 1000 mg/m2 | — |
| Subject | Onfekafusp alfa | Protein / enzyme biologic | 13 ug/kg | — |