drugset / Trial / NCT04733326

Evaluation of Post-operative Pain and Expression of IL-8 Using Ketolac or Cryoirrigation as a Final Flush in Single Visit Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis and Apical Periodontitis.Randomized Clinical Trial.

NCT04733326

Phase 1 Completed 48 enrolled Cairo University
RandomizedParallel-groupDouble-blindTreatment

Summary

To compare the effect of cryotherapy versus ketorolac tromethamine irrigating solutions used as a final flush in single visit endodontic treatment in mandibular molars, with symptomatic irreversible pulpitis and apical periodontitis on the: * Intensity of post-operative pain in patients with symptomatic irreversible pulpitis * Reduction of expression of Interleukin-8 (IL-8) post-instrumentation using ELISA * The analgesic intake following endodontic treatment for post-operative pain relief.

Timeline

Start
2021-09-01
Primary completion
2023-03-01
Completion
2023-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketorolac Tromethamine Small molecule 30 mg

Indications

No indication recorded.