drugset / Trial / NCT04733326
Evaluation of Post-operative Pain and Expression of IL-8 Using Ketolac or Cryoirrigation as a Final Flush in Single Visit Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis and Apical Periodontitis.Randomized Clinical Trial.
RandomizedParallel-groupDouble-blindTreatment
Summary
To compare the effect of cryotherapy versus ketorolac tromethamine irrigating solutions used as a final flush in single visit endodontic treatment in mandibular molars, with symptomatic irreversible pulpitis and apical periodontitis on the: * Intensity of post-operative pain in patients with symptomatic irreversible pulpitis * Reduction of expression of Interleukin-8 (IL-8) post-instrumentation using ELISA * The analgesic intake following endodontic treatment for post-operative pain relief.
Timeline
- Start
- 2021-09-01
- Primary completion
- 2023-03-01
- Completion
- 2023-03-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketorolac Tromethamine | Small molecule | 30 mg | — |
Indications
No indication recorded.