drugset / Trial / NCT04739774

Investigation of the Effect of Inhibition of CYP3A4/5 by Itraconazole on the PK of CHF6001 (Tanimilast)

NCT04739774

Phase 1 Completed 24 enrolled Chiesi Farmaceutici S.p.A.
Non-randomizedCrossoverOpen-labelOther

Summary

The objective of this proposed study is to investigate the pharmacokinetics interaction between CHF6001 as substrate and Itraconazole as inhibitor of CYP3A4/5 in a drug-drug interaction study.

Timeline

Start
2021-02-22
Primary completion
2021-04-20
Completion
2021-04-26

Drugs

EvaluationDrugModalityDoseRoute
Subject Itraconazole Small molecule Oral
Subject TRANIMILAST Small molecule