drugset / Trial / NCT04741984
Monocyte Antigen Carrier Cells for Newly Diagnosed GBM
NaSequentialOpen-labelTreatment
Summary
The primary purpose of this study is to determine the maximum tolerated dose (MTD) of MT-201-GBM (pp65CMV antigen monocytes) that will be administered to patients newly diagnosed with a type of brain tumor called glioblastoma (GBM) that has an unmethylated MGMT (O\[6\]-methylguanine-DNA methyltransferase) (MGMT) gene promoter.
Timeline
- Start
- 2023-08
- Primary completion
- 2025-05
- Completion
- 2025-11
Outcome
Outcome not reported
Stopped: “Due to need to proceed with procedural changes with goals of improving the technical and economic feasibility.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | MT-201-GBM | Vaccine | — | Intravenous |