drugset / Trial / NCT04741984

Monocyte Antigen Carrier Cells for Newly Diagnosed GBM

NCT04741984 ↗

NaSequentialOpen-labelTreatment

Summary

The primary purpose of this study is to determine the maximum tolerated dose (MTD) of MT-201-GBM (pp65CMV antigen monocytes) that will be administered to patients newly diagnosed with a type of brain tumor called glioblastoma (GBM) that has an unmethylated MGMT (O\[6\]-methylguanine-DNA methyltransferase) (MGMT) gene promoter.

Timeline

Start
2023-08
Primary completion
2025-05
Completion
2025-11

Outcome

Outcome not reported

Stopped: “Due to need to proceed with procedural changes with goals of improving the technical and economic feasibility.”

Drugs

EvaluationDrugModalityDoseRoute
Subject MT-201-GBM Vaccine — Intravenous

Indications