drugset / Trial / NCT04742595

Viral Specific T Cell Therapy for COVID-19 Related Pneumonia

NCT04742595 ↗

Phase 0 Completed 32 enrolled M.D. Anderson Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

This early phase I trial identifies the feasibility, possible benefits and/or side effects of administering SARS-CoV-2 specific cytotoxic T lymphocytes (CTLs) in treating cancer patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the virus responsible for coronavirus disease 2019 (COVID-19). SARS-CoV-2 Specific CTLs are a type of immune cells that are made from donated blood cells grown in the laboratory and are designed to kill cells infected with SARS-CoV-2 virus. Giving CTLs may help control the COVID-19 in cancer patients.

Timeline

Start
2020-12-18
Primary completion
2024-09-20
Completion
2024-09-20

Drugs

EvaluationDrugModalityDoseRoute
Subject SARS-CoV-2 Antigen-specific Cytotoxic T-lymphocytes Unknown — Intravenous