drugset / Trial / NCT04747574

Evaluation of the Safety of CD24-Exosomes in Patients With COVID-19 Infection

NCT04747574 ↗

Phase 1 Unknown 35 enrolled Tel-Aviv Sourasky Medical Center
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label Phase I study, four dose escalation groups, to evaluate the safety of CD24-exosomes in patients with moderate/severe COVID-19 disease. Patients with moderate/severe COVID-19 infection and factors predictive of a cytokine storm are recruited from the Corona department of the Tel Aviv Sourasky Medical Center (TASMC), who have provided informed consent are being recruited in four dose groups who will receive the exosome treatment as an add-on treatment to standard treatment.

Timeline

Start
2020-09-25
Primary completion
2021-02-25
Completion
2021-03-25

Drugs

EvaluationDrugModalityDoseRoute
Subject EXO-CD24 Other / unclassified 1e+08 unknown Inhaled
Subject EXO-CD24 Other / unclassified 5e+08 unknown Inhaled
Subject EXO-CD24 Other / unclassified 1e+09 unknown Inhaled
Subject EXO-CD24 Other / unclassified 1e+10 unknown Inhaled

Indications