drugset / Trial / NCT04758897
Clinical Study of VG161 in Subjects With Advanced Malignant Solid Tumors
NaSingle-groupOpen-labelTreatment
Summary
VG161 is a recombinant human-IL12/15/PDL1B oncolytic HSV-1 Injectable. This Phase I study will be conducted in HSV-seropositive subjects with advanced malignant solid tumors that are refractory to conventional therapies. This is an open label study to determine the safety and tolerability of VG161, and recommended dose of VG161 for Phase II trials.
Timeline
- Start
- 2021-04-14
- Primary completion
- 2022-03-14
- Completion
- 2022-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | VG161 | Unknown | 5e+07 unknown | Other |
| Subject | VG161 | Unknown | 1e+08 unknown | Other |
| Subject | VG161 | Unknown | 2e+08 unknown | Other |