drugset / Trial / NCT04758897

Clinical Study of VG161 in Subjects With Advanced Malignant Solid Tumors

NCT04758897

Phase 1 Unknown 18 enrolled CNBG-Virogin Biotech (Shanghai) Ltd.
NaSingle-groupOpen-labelTreatment

Summary

VG161 is a recombinant human-IL12/15/PDL1B oncolytic HSV-1 Injectable. This Phase I study will be conducted in HSV-seropositive subjects with advanced malignant solid tumors that are refractory to conventional therapies. This is an open label study to determine the safety and tolerability of VG161, and recommended dose of VG161 for Phase II trials.

Timeline

Start
2021-04-14
Primary completion
2022-03-14
Completion
2022-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject VG161 Unknown 5e+07 unknown Other
Subject VG161 Unknown 1e+08 unknown Other
Subject VG161 Unknown 2e+08 unknown Other

Indications