drugset / Trial / NCT04760496

Effect of Increased Oxytocin Doses on the Mode of Delivery in Obese Primiparous Women With Spontaneous or Induced Labour

NCT04760496

Phase 4 Completed 443 enrolled Assistance Publique - Hôpitaux de Paris
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The rate of caesarean section is higher among obese pregnant women, leading to increased morbidity in this already vulnerable population. Oxytocin is the main drug used in obstetrics to optimize progress of labour, but observational studies have suggested that its efficiency may be insufficient in obese women with usual doses. We design a randomised controlled trial to test the effect of an increased oxytocin dose on the rate of caesarean section in obese primiparous women with spontaneous or induced labour.

Timeline

Start
2021-10-02
Primary completion
2024-12-30
Completion
2025-01-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Oxytocin Peptide 2 unknown Intravenous
Subject Oxytocin Peptide 4 unknown Intravenous

Indications