PTH Analog Type II Odontoid Fracture

Phase 2 Terminated 22 enrolled David Lunardini University of Vermont · collab

Non-randomizedSingle-groupSingle-blindTreatment

Summary

This is a prospective cohort study with a historical control group involving patients \>=50 years-old with an acute (\<3 weeks) Anderson \& D'Alonzo type II dens fractures identified on cervical spine CT scan. This will be a pilot efficacy trial to compare treatment of odontoid fractures with 8 weeks of treatment with a parathyroid hormone analog (PTH) analog (abaloparatide) + hard collar immobilization in comparison to historical treatment with hard collar immobilization alone.

Timeline

Start: 2022-05-18
Primary completion: 2023-08-14
Completion: 2023-08-14

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Abaloparatide	Peptide	80 ug	Subcutaneous

Indications

No indication recorded.