drugset / Trial / NCT04761887

Cool Pre-operative TAP Blocks

NCT04761887

Phase 1 Withdrawn Daniel Wambold
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This is a pilot study of approximately 20 pre-operative patients scheduled for a transversus abdominis plane (TAP) block as pain management for a previously scheduled surgery. Subjects will be randomly assigned to receive either cooled ropivacaine (4°C) during a TAP block or room temperature (between 20-25°C) ropivacaine during the block. The effects of a TAP block generally diminish within 24 hours. We believe that cooling ropivacaine before administration may slightly prolong the analgesic effects of the block and delay time before additional analgesic is requested, resulting in less opioid use following surgery.

Timeline

Start
2022-12
Primary completion
2022-12
Completion
2023-03

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ropivacaine Other / unclassified Other

Indications

No indication recorded.