drugset / Trial / NCT04762199

MRX-2843 and Osimertinib for the Treatment of Advanced EGFR Mutant Non-small Cell Lung Cancer

NCT04762199

NaSingle-groupOpen-labelTreatment

Summary

This phase Ib trial evaluates the best dose and side effects of MRX-2843 when given in combination with osimertinib in treating patients with EGFR gene mutant non-small cell lung cancer that has spread to other places in the body (advanced). MRX-2843 and osimertinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2021-02-24
Primary completion
2026-12-27
Completion
2026-12-27

Drugs

EvaluationDrugModalityDoseRoute
Subject MRX-2843 Unknown Oral
Subject Osimertinib Small molecule Oral