drugset / Trial / NCT04764058
Efficacy and Safety of Colistin Based Antibiotic Therapy
RandomizedParallel-groupOpen-labelOther
Summary
To evaluate the efficacy and safety of antibiotic combinations containing Colistin in the treatment of children with multidrug-resistant gram negative infections admitted in the pediatric surgery intensive care unit. The main outcome measure is clinical and microbiological responses to therapy. The secondary outcome is the occurrence of adverse events during Colistin combination treatment.
Timeline
- Start
- 2017-09-01
- Primary completion
- 2019-09-01
- Completion
- 2021-09-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Cilastatin | Small molecule | — | Intravenous |
| Background | IMIPENEM ANHYDROUS | Small molecule | 15 mg/kg | Intravenous |
| Background | IMIPENEM ANHYDROUS | Small molecule | 25 mg/kg | Intravenous |