Renin Angiotensin System Blockade in Renal Transplant Patients With Presence of PECs in Urine

Summary

By means of a personalized medicine strategy, investigators are going to evaluate if the treatment with an angiotensin II receptor antagonist (ARAII) in renal transplant patients with the presence of renal progenitor cells (PECs) in the urine is able to prevent the expected loss of glomerular filtration (GFR) observed in this subgroup of patients. In addition, investigators intend to deepen the mechanisms of glomerular damage and glomerular repair involved in the process of chronic allograft damage.

Timeline

Start

2020-02-19

Primary completion

2023-06

Completion

2023-06

Drugs

Indications