drugset / Trial / NCT04770545

An Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan (APL-2) in Subjects With Geographic Atrophy Secondary to AMD

NCT04770545

Phase 3 Completed 792 enrolled Apellis Pharmaceuticals, Inc.
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This is a phase 3, open-label, multicenter, extension study to evaluate the long-term safety and efficacy of pegcetacoplan (APL-2) in subjects with geographic atrophy (GA) secondary to age-related macular degeneration (AMD) who participated in Study APL2-103 (NCT03777332) or completed the treatment at Month 24 of either Study APL2-303 (Derby, NCT03525613) or Study APL2-304 (Oaks, NCT03525600).

Timeline

Start
2021-03-04
Primary completion
2025-09-05
Completion
2025-09-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Pegcetacoplan Peptide 15 mg Intravitreal