drugset

drugset / Trial / NCT04771676

Intraperitoneal Injection of Oncolytic Viruses H101 for Patients With Refractory Malignant Ascites

NCT04771676 ↗

Phase 2 Completed 25 enrolled Fudan University

NaSingle-groupOpen-labelTreatment

Summary

Assessment of effectiveness, safety and local immune activation of Oncolytic Viruses H101 in patients with refractory malignant ascites.

Timeline

Start: 2021-03-05
Primary completion: 2023-01-31
Completion: 2023-01-31

Publications

Zhang Y, Qian L, Chen K, Gu S, Meng Z, Wang J, Li Y, Wang P. Oncolytic adenovirus in treating malignant ascites: A phase II trial and longitudinal single-cell study. Mol Ther. 2024 Jun 5;32(6):2000-2020. doi: 10.1016/j.ymthe.2024.04.029. Epub 2024 Apr 24.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	H101	Other / unclassified	1.5e+12 unknown	Other

Indications