Azithromycin for Child Survival in Niger: Delivery Trial

Phase 4 Completed 10925 enrolled University of California, San Francisco Bill and Melinda Gates Foundation · collab Programme National de Santé Oculaire, Ministère de la Santé Publique du Niger · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

This cluster-randomized trial aims to compare the impact of different delivery approaches to azithromycin distribution on coverage, costs, and feasibility outcomes. The investigators hypothesize that door-to-door delivery will have higher coverage and costs and similar feasibility and acceptability compared to fixed-point delivery.

Timeline

Start: 2021-06-28
Primary completion: 2023-06-30
Completion: 2023-06-30

Publications

Arzika AM, Maliki R, Amza A, Karamba A, Gallo N, Aichatou B, Sara II, Beidi D, Haroun LM, Oumarou F, Lebas E, Peterson B, Colby E, Nguyen W, Liu Z, Fitzpatrick MC, Arnold BF, Lietman TM, O'Brien KS; AVENIR Study Group. Comparison of door-to-door and fixed-point delivery of azithromycin distribution for child survival in Niger: A cluster-randomized trial. PLOS Glob Public Health. 2023 Nov 15;3(11):e0002559. doi: 10.1371/journal.pgph.0002559. eCollection 2023.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Azithromycin	Small molecule	20 mg/kg	Oral

Indications

No indication recorded.