drugset

drugset / Trial / NCT04776135

Comparative Bioavailability Study of Oral Edaravone Administered Orally and Via a Nasogastric Tube

NCT04776135 ↗

Phase 1 Completed 36 enrolled Shionogi

RandomizedCrossoverOpen-labelOther

Summary

To investigate the comparative bioavailability of edaravone oral suspension administered orally and via a nasogastric tube in healthy adult subjects

Timeline

Start: 2021-02-26
Primary completion: 2021-04-01
Completion: 2021-04-16

Publications

Results Shimizu H, Nishimura Y, Shiide Y, Ueda M, Yokota S, Kato Y, Hirai M. Edaravone Administered Orally and Via Nasogastric Tube in Healthy Adults: A Comparative Bioavailability Phase 1 Study. Clin Pharmacol Drug Dev. 2023 Jan;12(1):77-84. doi: 10.1002/cpdd.1175. Epub 2022 Oct 12.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Edaravone	Unknown	—	Oral

Indications

No indication recorded.