drugset / Trial / NCT04778358

Higher Dose of Rekovelle in Oocyte Donors

NCT04778358

Phase 2 Completed 40 enrolled IVI Madrid
NaSingle-groupOpen-labelTreatment

Summary

Higher numbers of oocytes have not been shown to increase implantation or live newborn rates, but higher numbers of oocytes are likely to be beneficial in certain treatments. These clinical cases where a high ovarian response can be IVF cycles with genetic diagnosis, patients who need more than one pregnancy or, as in our case, oocyte donation. For this reason, and based on previous studies, investigators intend to increase the ovarian response by increasing the dose of follitropin. This clinical trial aims to evaluate high doses of Rekovelle (follitropin delta) to obtain an average of 17 oocytes in a population of oocyte donors, without affecting the health of the patients.

Timeline

Start
2021-09-28
Primary completion
2022-06-16
Completion
2022-06-16

Drugs

EvaluationDrugModalityDoseRoute
Subject Follitropin delta Protein / enzyme biologic 15 ug Subcutaneous

Indications

No indication recorded.