drugset / Trial / NCT04784442

A Dose-finding Trial of ETC-1002(Bempedoic Acid) in Patients With Hypercholesterolemia

NCT04784442

Phase 2 Completed 188 enrolled Otsuka Pharmaceutical Co., Ltd.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to assess the low-density lipoprotein cholesterol (LDL-C)-lowering efficacy and safety of ETC-1002(bempedoic acid) 60 mg, 120 mg and 180 mg versus placebo added to ongoing stable statin therapy or other lipid-modifying therapies in Japanese patients with hypercholesterolemia treated for 12 weeks.

Timeline

Start
2021-03-24
Primary completion
2022-04-18
Completion
2022-05-17

Drugs

EvaluationDrugModalityDoseRoute
Subject Bempedoic acid Small molecule 60 mg
Subject Bempedoic acid Small molecule 120 mg
Subject Bempedoic acid Small molecule 180 mg

Indications