drugset / Trial / NCT04787848
Chronic Widespread Pain in HIV: Novel Mechanisms and Therapeutics
RandomizedCrossoverOpen-labelBasic science
Summary
To determine if decreased production or release of endogenous opioid peptides by peripheral immune cells contributes to hypersensitivity in people with HIV
Timeline
- Start
- 2021-11-15
- Primary completion
- 2027-05-30
- Completion
- 2027-05-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methylnaltrexone | Other / unclassified | 0.15 mg/kg | — |
| Subject | Methylnaltrexone | Other / unclassified | 8 mg | — |
| Subject | Methylnaltrexone | Other / unclassified | 12 mg | — |