Sequential CD19 and CD22 CAR-T Therapy for Newly Diagnosed Ph+ B-ALL

Summary

Clinical Trial for the Efficacy and Safety of Sequential CD19 and CD22 CAR-T Therapy for Adult Patients With Newly Diagnosed Ph Chromosome Positive B-cell Acute Lymphoblastic Leukemia

Timeline

Start

2021-03-05

Primary completion

2024-08-31

Completion

2024-08-31

Publications

• Zhang M, Fu S, Feng J, Hong R, Wei G, Zhao H, Zhao M, Xu H, Cui J, Huang S, Wu X, Liu L, Sun J, Wu W, Zhu Y, He J, Zhao Y, Cai Z, Zheng W, Ye X, Shi J, Luo Y, Wang D, Chang AH, Hu Y, Huang H. Dasatinib and CAR T-Cell Therapy in Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: A Nonrandomized Clinical Trial. JAMA Oncol. 2025 Jun 1;11(6):625-629. doi: 10.1001/jamaoncol.2025.0674.

Drugs

Indications