drugset / Trial / NCT04788641
Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy Subjects
RandomizedCrossoverOpen-labelTreatment
Summary
This study will be an open-label, randomised sequence, 2-period, 2-cohort, 2-treatment in each cohort, cross-over study in healthy subjects (males and females of non-childbearing potential), performed at a single study centre.
Timeline
- Start
- 2021-03-30
- Primary completion
- 2021-09-16
- Completion
- 2021-09-16
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclosporine | Peptide | — | Oral |
| Subject | Sodium Zirconium Cyclosilicate | Other / unclassified | — | Oral |
| Subject | Tacrolimus | Small molecule | — | Oral |
Indications
No indication recorded.