Clinical Trial of Solriamfetol for Excessive Sleepiness Related to Shift Work Disorder

Summary

In this research study the investigators want to learn more about whether the medication Solriamfetol improves daytime sleepiness in workers who start work at very early times (between 3 and 6am).

Timeline

Start

2021-07-21

Primary completion

2024-04-06

Completion

2024-04-19

Publications

• Zitting KM, Gilmore KR, Lockyer BJ, Leary EB, Wang W, Issa NC, Quan SF, Williams JS, Duffy JF, Czeisler CA. Solriamfetol for Excessive Sleepiness in Early-Morning Shift Work Disorder. NEJM Evid. 2026 Feb;5(2):EVIDoa2500190. doi: 10.1056/EVIDoa2500190. Epub 2026 Jan 27.

Drugs

Indications