Hypertonic Dextrose Versus Corticosteroid Intra-Articular Injections for the Treatment of Trapeziometacarpal Arthritis

Phase 3 Unknown 130 enrolled Christine M. Kleinert Institute for Hand and Microsurgery Kleinert, Kutz and Associates · collab

RandomizedParallel-groupDouble-blindTreatment

Summary

The evolving reports form recent studies are creating a promise on the potential use of dextrose injections for treating arthritis and replacing current method of treating early osteoarthritis by corticosteroids by giving long standing effect and improving patients' symptoms and function. Over the past 5 years, an increasing number of level I and level II studies have emerged, examining the effect of intra-articular prolotherapy for the treatment of both hip and knee osteoarthritis. On the contrary, there is limited data in small joints, such as the temporomandibular joint.

Timeline

Start: 2021-04-01
Primary completion: 2022-03-01
Completion: 2022-07-01

Publications

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Dextrose	Unknown	15 %	Other
Comparator	Methylprednisolone	Other / unclassified	40 mg/ml	Other

Indications

No indication recorded.