drugset / Trial / NCT04792073
Study of Avelumab and/or Radiation Therapy in People With Advanced Merkel Cell Carcinoma
Phase 2
Active not recruiting
18 enrolled
Memorial Sloan Kettering Cancer Center
EMD Serono · collab
NaSingle-groupOpen-labelTreatment
Summary
This study will test the use of comprehensive ablative radiation therapy (CART), with the immunotherapy drug avelumab, in people with Merkel cell carcinoma (MCC) that has progressed after treatment and cannot be removed with surgery. The study researchers want to find out if CART works well when combined with avelumab.
Timeline
- Start
- 2021-03-08
- Primary completion
- 2027-03
- Completion
- 2027-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Avelumab | Monoclonal antibody | 800 mg | Intravenous |