drugset / Trial / NCT04795466

Study of the Efficacy and Safety of Various Anti-inflammatory Agents in Participants With Mild Cognitive Impairment or Mild Alzheimer's Disease

NCT04795466

Phase 2 Terminated 34 enrolled Novartis Pharmaceuticals
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this platform study was to evaluate the effect of anti-inflammatory agents on cognition in early Alzheimer's disease. Additionally, the safety and tolerability and their effects on central and peripheral inflammation were evaluated. Due to early termination only a single agent could be studied.

Timeline

Start
2021-10-28
Primary completion
2024-03-07
Completion
2024-03-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Canakinumab Monoclonal antibody 300 mg Subcutaneous