drugset / Trial / NCT04798612
Effect of Low-dose Interferon-alfa2a on Peri-operative Immune Suppression
RandomizedParallel-groupDouble-blindTreatment
Summary
The aim of this randomized double-blinded placebo-controlled phase 2 study is to determine efficacy of preoperative treatment with interferon-alfa2a in patients with pMMR colon cancer on perioperative immune suppression and infiltration of lymphocytes in the primary tumor.
Timeline
- Start
- 2023-08-14
- Primary completion
- 2025-08-01
- Completion
- 2025-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Peginterferon alfa-2a | Protein / enzyme biologic | 45 ug | Subcutaneous |