drugset / Trial / NCT04798612

Effect of Low-dose Interferon-alfa2a on Peri-operative Immune Suppression

NCT04798612

RandomizedParallel-groupDouble-blindTreatment

Summary

The aim of this randomized double-blinded placebo-controlled phase 2 study is to determine efficacy of preoperative treatment with interferon-alfa2a in patients with pMMR colon cancer on perioperative immune suppression and infiltration of lymphocytes in the primary tumor.

Timeline

Start
2023-08-14
Primary completion
2025-08-01
Completion
2025-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Peginterferon alfa-2a Protein / enzyme biologic 45 ug Subcutaneous

Indications