drugset / Trial / NCT04800081

Effect of LCZ696 on Urinary Microalbumin and Pulse Wave Velocity in Perimenopausal Patients With Hypertension

NCT04800081

Unknown 264 enrolled LanZhou University
RandomizedParallel-groupOpen-labelTreatment

Summary

To explore the efficacy of Sacubitril/Valsartan in the treatment of perimenopausal hypertensive patients, as well as the difference between the antihypertensive efficacy and valsartan, the therapeutic effect of its exposure to different factors and the protection of target organs.To provide reference for the clinical treatment of perimenopausal hypertension patients with shakubactrivalsartan. 1. To evaluate the effects of Sacubitril/Valsartan on urinary microalbumin and pulse wave velocity in perimenopausal hypertension patients. 2. To evaluate the clinical application of Sacubitril/Valsartan in the treatment of perimenopausal hypertension, so as to improve the blood pressure management ability and control rate of patients with such hypertension.

Timeline

Start
2020-07-09
Primary completion
2021-06-09
Completion
2021-07-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Sacubitril/Valsartan Unknown 100 mg
Subject Sacubitril/Valsartan Unknown 400 mg
Comparator Valsartan Small molecule 80 mg
Comparator Valsartan Small molecule 320 mg