IIT PH1 KDS-1001 in Patients With CML

Summary

This open label, non-randomized, prospective phase I study is designed to evaluate if the addition of natural killer cell therapy (KDS-1001) to tyrosine kinase inhibitors (TKIs) for chronic myeloid leukemia (CML) patients with persistent or recurrent molecular residual disease (MRD) after at least one year of TKI therapy will allow patients to achieve RT-PCR negativity (MRD negative). This may have implications for future TKI cessation studies.

Timeline

Start

2024-12

Primary completion

2027-12

Completion

2029-12

Outcome

Outcome not reported

Stopped (Enrollment): “Study halted prematurely, prior to enrollment of first participant.”

Drugs

Indications