drugset / Trial / NCT04808648
The Effect of Itraconazole and Rifampicin on the Pharmacokinetics of SH-1028
Non-randomizedParallel-groupOpen-labelOther
Summary
This is a phase I study to assess the drug-drug interaction of SH-1028 tablets and Itraconazole/Rifampicin tablets. The study also evaluates the pharmacokinetic and tolerability of SH-1028 tablets in healthy subjects. This study provides evidence for the designing of following clinical trial protocols.
Timeline
- Start
- 2021-04-06
- Primary completion
- 2021-06-10
- Completion
- 2021-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Itraconazole | Small molecule | 200 mg | Oral |
| Subject | ORITINIB | Small molecule | 200 mg | Oral |
| Subject | Rifampin | Small molecule | 600 mg | Oral |
Indications
No indication recorded.