drugset / Trial / NCT04813471
Managing Endothelial Dysfunction in Critically Ill COVID-19 Patients at LAUMCRH
RandomizedParallel-groupOpen-labelTreatment
Summary
COVID-19 Infection has been found to cause endothelial dysfunction and most of the adverse events stem to this mechanism. So we seek to target endothelial dysfunction in critically Ill patients with covid by giving them an endothelial protocol ( L-arginine, Folic Acid, Statin, Nicorandil, Vitamin B complex) and monitor clinical outcome in those patients.
Timeline
- Start
- 2021-01-20
- Primary completion
- 2021-03-20
- Completion
- 2021-04-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Atorvastatin | Small molecule | 40 mg | Oral |
| Subject | L-arginine | Small molecule | 1 g | Oral |
| Subject | Nicorandil | Other / unclassified | 20 mg | Oral |
| Subject | Vitamin B Complex | Unknown | 1 unknown | Intravenous |
| Subject | folic acid | Other / unclassified | 5 mg | Oral |