drugset / Trial / NCT04828005
Pharmacodynamic Evaluation of Intranasal Nalmefene
RandomizedCrossoverOpen-labelBasic science
Summary
This study is to determine the pharmacodynamics (the effects of the drug and mechanisms of their action within the body) of Nalmefene when given intranasally (IN; into the nose) compared to intranasal naloxone when given to healthy volunteers under steady state opioid agonism.
Timeline
- Start
- 2021-03-30
- Primary completion
- 2022-03-14
- Completion
- 2022-03-14
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nalmefene | Small molecule | 3 mg | Intranasal |
| Comparator | Naloxone | Small molecule | 4 mg | Intranasal |
Indications
No indication recorded.