drugset / Trial / NCT04834791

Letrozole Versus Gonadotropins in Clomiphene Citrate Resistance

NCT04834791

Phase 4 Completed 70 enrolled Tanta University
RandomizedParallel-groupOpen-labelTreatment

Summary

Clomiphene citrate resistance (CCR) occur in 15-40% in women with PCOS. Several studies have shown that letrozole is superior to CC regarding side effects, ovulation, and pregnancy rates. Letrozole or gonadotropins use for ovulation induction in CCR is not well established which is superior and most safe.

Timeline

Start
2019-03-01
Primary completion
2019-10-31
Completion
2019-10-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bravelle Unknown 75 unknown Intramuscular
Subject Letrozole Other / unclassified 2.5 mg Oral

Indications