drugset / Trial / NCT04838405
A Study of CT-388 in Otherwise Healthy Overweight and Obese Adults and Patients With Type 2 Diabetes Mellitus
RandomizedSequentialTriple-blindTreatment
Summary
This is a first-in-human evaluation of CT-388 in a double blind, placebo controlled, randomized, SAD/MAD/MD, safety, tolerance, PK, and PD study when administered as a SC injection in otherwise healthy overweight and obese adult participants and obese participants with T2DM.
Timeline
- Start
- 2021-04-29
- Primary completion
- 2024-06-18
- Completion
- 2024-08-02
Outcome
Met primary endpoint
release “CT-388 over 24 weeks resulted in significant weight loss in healthy adults with obesity compared to placebo.” gene.com ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | CT-388 | Peptide | — | Subcutaneous |