Efficacy and Safety of SHR-1314 in Patients With Active Ankylosing Spondylitis

Summary

The purpose of this study is to assess efficacy, safety, pharmacokinetics and immunogenicity of subcutaneous SHR-1314 in patients with active ankylosing spondylitis

Timeline

Start

2021-06-09

Primary completion

2023-11-03

Completion

2024-02-28

Publications

• Zhu J, Zhao C, Mi C, Liu S, Wu R, Li T, Duan X, Sun L, Yang L, He X, Liu W, Li Y, Ma L, Du H, Liu Y, Chen G, Zhang H, Wang T, Liu X, Shi X, Liu J, Wu H, Sun H, Xue Y, Chai K, Li H, Hu J, Dong F, Lin L, Du Q, Bai X, Huang F. Vunakizumab for Radiographic Axial Spondyloarthritis: A Randomized Clinical Trial. JAMA Netw Open. 2026 May 1;9(5):e2611632. doi: 10.1001/jamanetworkopen.2026.11632.

Drugs

Indications